ISSN 1662-4009 (online)

ey0016.10-9 | (1) | ESPEYB16

10.9. Continuous glucose monitoring and glycemic control among youth with type 1 diabetes: International comparison from the T1D Exchange and DPV Initiative

DJ DeSalvo , KM Miller , JM Hermann , DM Maahs , SE Hofer , MA Clements , E Lilienthal , JL Sherr , M Tauschmann , RW Holl , Exchange DPV Registries T1D

To read the full abstract: Pediatr Diabetes. 2018;19:1271–1275New technologies such as continuous glucose monitoring, insulin pumps and closed-loop systems are likely to change diabetes care and hopefully will reduce the burden of disease management, decrease diabetes associated comorbidities, and increase life expectancy.To assess the change in rates of pedia...

ey0020.8-1 | Clinical Trials – New Treatments | ESPEYB20

8.1. Effect of Verapamil on pancreatic beta cell function in newly diagnosed pediatric type 1 diabetes: A randomized clinical trial

GP Forlenza , J McVean , RW Beck , C Bauza , R Bailey , B Buckingham , LA DiMeglio , JL Sherr , M Clements , A Neyman , C Evans-Molina , EK Sims , LH Messer , L Ekhlaspour , R McDonough , M Van Name , D Rojas , S Beasley , S DuBose , C Kollman , A Moran , CLVer Study Group

Brief summary: In this double-blind, randomized clinical trial conducted in 6 US centres, 88 children and adolescents (aged 7–17 years) with newly diagnosed type 1 diabetes (T1D) were randomized to either once-daily oral verapamil or placebo, within 1 month from diagnosis. Treatment with verapamil led to better stimulated C-peptide secretion at 52 weeks post-diagnosis, with levels 30% higher compared to placebo.Verapamil is a calcium channel blocker...